The Celtic full-back has been struggling against a hamstring strain for the last month and has been ruled out after further tests yesterday.
Izaguirre will return home to Honduras to rest the injury before rejoining Celtic for pre-season training.
Honduras boss Fernando Suarez said: “Emilio had been complaining of muscle spasms in his leg in training and was sent to a clinic in Houston for tests.
“Those tests have revealed he has a hamstring tear and has been advised to rest for at least a month. It’s a shame for him because he loves playing for his country.”
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