Neil Lennon has made four changes to the Celtic side to face Ross County but there is no place in the 20 man squad for Leigh Griffiths.
Vasilis Barkas, Nir Bitton, Tom Rogic and Albian Ajeti come into the starting XI with Scott Bain, Olivier Ntcham, Callum McGregor and Moi Elyounoussi dropping onto the bench.
There is still no sign of Karamoko Dembele in the squad with Tony Ralston and Ewan Henderson listed among the substitutes.
Celtic go into the match looking to lift the trophy for the fifth year in succession, a run that started in August 2016 with a 5-0 win at home to Motherwell.
Ross County were the last team to beat Celtic in the tournament, earlier in 2016 in a Hampden semi-final when Ronny Deila was in charge.
Celtic won 5-0 away to Ross County in September with a similar type of result needed to ease some of the pressure away from Lennon ahead of an ominous midweek trip to the San Siro to take on AC Milan in the doomed Europa League campaign.
CELTIC: Barkas; Elhamed, Jullien, Ajer, Laxalt: Christie, Bitton, Brown; Rogic; Edouard, Ajeti
SUBS: Bain, Taylor, Duffy, Klimala, Ntcham, Elyounoussi, McGregor, Henderson, Ralston
